Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292586 | 1.00 | SCN9A (0.44) | SCN9ACYP2C9CFTRHPGDNPC1 | |
| SCHEMBL28941110 | 0.82 | CFTR (0.38) | SCN9ACYP2C9CFTRHPGDADORA2A | |
| SCHEMBL28940917 | 0.82 | CFTR (0.38) | SCN9ACYP2C9CFTRHPGDADORA2A | |
| SCHEMBL28292566 | 0.81 | MAOB (0.49) | SCN9AMAOB | |
| SCHEMBL28963812 | 0.81 | SCN9A (0.40) | SCN9ACYP2C9CFTRHPGDNPC1 | |
| SCHEMBL28940983 | 0.81 | SCN9A (0.40) | SCN9ACYP2C9CFTRHPGDNPC1 | |
| SCHEMBL28292577 | 0.80 | CCNC (0.48) | SCN9ACYP2C9CFTRHPGDMAOB | |
| SCHEMBL20929477 | 0.79 | ADORA2A (0.44) | SCN9AMAOBADORA2AADORA1PARP1 | |
| SCHEMBL28284688 | 0.79 | CCNC (0.43) | CYP2C9HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28294317 | 0.78 | SCN9A (0.45) | SCN9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |