Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294317 | 0.85 | SCN9A (0.45) | MAOBHIF1ASCN9A | |
| SCHEMBL12923703 | 0.82 | PDE10A (0.53) | MAOBMMP13HIF1APDE10AL3MBTL1 | |
| SCHEMBL28940971 | 0.82 | MMP13 (0.37) | MAOBMMP13CNR1MAPTL3MBTL1 | |
| SCHEMBL28292577 | 0.82 | CCNC (0.48) | MAOBSCN9AL3MBTL1 | |
| SCHEMBL28940932 | 0.81 | CNR2 (0.49) | MAOBSCN9AMAPTL3MBTL1 | |
| SCHEMBL28940985 | 0.81 | SCN9A (0.44) | MAOBSCN9A | |
| SCHEMBL28292586 | 0.81 | SCN9A (0.44) | MAOBSCN9A | |
| SCHEMBL28284688 | 0.80 | CCNC (0.43) | CNR1PDE10AMAPT | |
| SCHEMBL28292579 | 0.79 | CNR2 (0.50) | MAOBSCN9ACNR1 | |
| SCHEMBL12896110 | 0.78 | KMT2A (0.46) | MAOBMMP13CNR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |