Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292577 | 0.87 | CCNC (0.48) | SCN9AMAOBCCNCCDK8CDK19 | |
| SCHEMBL28292566 | 0.85 | MAOB (0.49) | SCN9AMAOBHIF1A | |
| SCHEMBL28941005 | 0.84 | SCN9A (0.38) | SCN9AMAOBCYP4F2CYP4A11 | |
| SCHEMBL28292627 | 0.82 | SCN9A (0.41) | SCN9AKMT2ACYP4F2CYP4A11 | |
| SCHEMBL28940932 | 0.81 | CNR2 (0.49) | SCN9AMAOBCCNCCDK8CDK19 | |
| SCHEMBL28940894 | 0.78 | CCNC (0.39) | SCN9AMAOBCCNCCDK8CDK19 | |
| SCHEMBL28940985 | 0.78 | SCN9A (0.44) | SCN9AMAOB | |
| SCHEMBL28292586 | 0.78 | SCN9A (0.44) | SCN9AMAOB | |
| SCHEMBL28284688 | 0.78 | CCNC (0.43) | CCNCCDK8CDK19KMT2A | |
| SCHEMBL22341942 | 0.74 | P4HTM (0.46) | MAOBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |