Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941993 | 0.87 | MAPT (0.50) | NPSR1EPHX2MAPTNPC1RAB9A | |
| SCHEMBL24534568 | 0.86 | NPC1 (0.49) | NPC1RAB9ACRHBPCRHR2TRPV1 | |
| SCHEMBL28941997 | 0.85 | MAPT (0.51) | NPSR1EPHX2PPARGMAPTSMN1; SMN2 | |
| SCHEMBL28941990 | 0.85 | ALDH1A1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28941994 | 0.82 | SMN1; SMN2 (0.57) | EPHX2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL840765 | 0.82 | NPSR1 (0.54) | NPSR1EPHX2PPARGMAPTCRHBP | |
| SCHEMBL28499074 | 0.82 | SMN1; SMN2 (0.60) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| Benzene SCHEMBL28007806 | 0.81 | KMT2A (0.56) | NPSR1EPHX2PPARGMAPTNPC1 | |
| SCHEMBL859597 | 0.79 | CES2 (0.60) | NPSR1EPHX2PPARGMAPTCRHBP | |
| SCHEMBL16399046 | 0.78 | NPSR1 (0.53) | NPSR1EPHX2PPARGMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |