Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 4/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363504 | 0.86 | PKM (0.50) | RAB9ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL28941981 | 0.86 | PKM (0.50) | RAB9ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL28941994 | 0.85 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2TSHRATMALDH1A1 | |
| SCHEMBL10347454 | 0.81 | ABCB1 (0.43) | ABCB1RAB9AGRNSORT1SMN1; SMN2 | |
| SCHEMBL28499074 | 0.78 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2TSHRATMALDH1A1 | |
| SCHEMBL28941990 | 0.78 | ALDH1A1 (0.50) | RAB9ASMN1; SMN2TSHRATMALDH1A1 | |
| SCHEMBL28941997 | 0.76 | MAPT (0.51) | SMN1; SMN2ALDH1A1GAATDP1MAPT | |
| SCHEMBL1704844 | 0.75 | ABCB1 (0.47) | ABCB1SMN1; SMN2ATMALDH1A1GPR35 | |
| SCHEMBL28941993 | 0.75 | MAPT (0.50) | RAB9ASMN1; SMN2TSHRATMALDH1A1 | |
| SCHEMBL28963867 | 0.74 | NPC1 (0.51) | RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |