Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473539 | 0.95 | KAT8 (0.56) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL28182972 | 0.93 | KAT8 (0.55) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5272268 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5274232 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL2821516 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5271556 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL6434109 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL6435534 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5273325 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5271367 | 0.93 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723747-B1 | THE COMBINATION COMPRISING ADAPALENE AND BENZOYL PEROXIDE | SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) | 2023-11-22 | — | — | EP | claimed |
| EP-2544660-B1 | RIFAXIMIN READY-TO-USE SUSPENSION | LUPIN LTD (IN) | 2018-06-13 | — | — | EP | claimed |
| EP-1012225-A4 | BEER SPOILAGE REDUCING METHODS AND COMPOSITIONS | STATE OF OREGONACTING BY AND T (US) | 2004-04-07 | — | — | EP | claimed |
| EP-1012225-A1 | BEER SPOILAGE REDUCING METHODS AND COMPOSITIONS | THE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATEBOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1999007821-A1 | BEER SPOILAGE REDUCING METHODS AND COMPOSITIONS | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 1999-02-18 | — | — | WO | claimed |
| US-4302439-A | Method of disclosing dental plaque with D and C Red 33 | SELWYN STEPHEN L | 1981-11-24 | — | — | US | claimed |
| CN-118924714-B | MK-7-containing pharmaceutical composition, application and preparation method thereof | 广东新达瑞生物科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-118924714-A | MK-7-containing pharmaceutical composition, application and preparation method thereof | 广东新达瑞生物科技有限公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024174962-A1 | EG017 OINTMENT | 长春金赛药业有限责任公司 | 2024-08-29 | — | — | WO | disclosed |
| US-20240207189-A1 | LIQUID CLONIDINE EXTENDED RELEASE COMPOSITION | TRIS PHARMA, INC (US) | 2024-06-27 | — | — | US | disclosed |
| US-11918689-B1 | Liquid clonidine extended release composition | TRIS PHARMA INC (US) | 2024-03-05 | — | — | US | disclosed |
| WO-2023147443-A2 | NOVEL COMPOSITIONS | TULEX PHARMACEUTICALS INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20230165837-A1 | NOVEL CLONIDINE FORMULATION | PROVIDENT BANK | 2023-06-01 | — | — | US | disclosed |
| EP-0244177-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0224177-A2 | Aqueous bath and process for improving the properties of photographic-recording materials | Agfa-Gevaert AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0206148-A2 | Stabilizing bath and process for preparing photographic images | Agfa-Gevaert AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| CN-85109275-A | ORAL COMPOSITION | — | 1986-06-10 | — | — | CN | disclosed |
| US-4302439-A | Method of disclosing dental plaque with D and C Red 33 | SELWYN STEPHEN L | 1981-11-24 | — | — | US | disclosed |
| US-4140836-A | PRIMERS, WATERPROOFING, ADHESION | PPG INDUSTRIES, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4098740-A | PRIMER COATINGS, POLYEPOXIDES, PHENOLS | PPG INDUSTRIES, INC. (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165837-A1 | NOVEL CLONIDINE FORMULATION | SLC18A1, SLC6A2, SLC18A2 | KAT8 3951/4885BID 2624/4885MCL1 4627/4885 |
| US-11918689-B1 | Liquid clonidine extended release composition | SLC18A1, SLC18A2, CRH | KAT8 3893/4885BID 3731/4885MCL1 4212/4885 |
| US-20240207189-A1 | LIQUID CLONIDINE EXTENDED RELEASE COMPOSITION | SLC18A1, SLC18A2, CRH | KAT8 3893/4885BID 3731/4885MCL1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.