Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772588 | 0.89 | FABP4 (0.31) | PDE6DKMT2A | |
| SCHEMBL27772693 | 0.86 | KMT2A (0.34) | RORCRARGPDE6DMAPTPKM | |
| SCHEMBL27772599 | 0.83 | PDE6D (0.35) | NOTUMPDE6DMAPTKMT2ARAB9A | |
| SCHEMBL28781970 | 0.80 | KMO (0.36) | MAPTKMT2A | |
| SCHEMBL27772708 | 0.79 | HTT (0.35) | KRASMAPTKMT2A | |
| SCHEMBL27793932 | 0.77 | MAPT (0.36) | MAPTKMT2A | |
| SCHEMBL27793982 | 0.77 | RARG (0.36) | RORCRARGPDE6DMAPTPKM | |
| SCHEMBL28944692 | 0.76 | MAPT (0.39) | MAPT | |
| SCHEMBL28781989 | 0.76 | MKNK2 (0.34) | MAPT | |
| SCHEMBL28785086 | 0.76 | CDC7 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |