Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
| ▸ | SDHA | P31040 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671471 | 0.86 | MEN1 (0.33) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL27638668 | 0.86 | ALDH1A1 (0.32) | ALDH1A1LMNAMAOAPTGS1MAOB | |
| SCHEMBL27659475 | 0.78 | AKR1C3 (0.39) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL1911899 | 0.69 | MAPT (0.53) | TP53ALDH1A1MAPTGAATSHR | |
| SCHEMBL8305482 | 0.66 | F10 (0.47) | TP53ALDH1A1KMT2AKDM4E | |
| SCHEMBL27546292 | 0.65 | NPC1 (0.49) | TP53ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL8256507 | 0.65 | SCN9A (0.43) | TP53ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL17195404 | 0.65 | ALDH1A1 (0.40) | TP53ALDH1A1MAPTGAATSHR | |
| SCHEMBL12583478 | 0.63 | ADRB1 (0.47) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL19998610 | 0.63 | HPGD (0.47) | TP53ALDH1A1MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679415-B | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101679415-A | oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD | 2010-03-24 | — | — | CN | disclosed |