Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944892 | 1.00 | CA2 (0.48) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL24469448 | 0.89 | NOD1 (0.42) | NOD1KMT2APPARDPOLBFOLH1 | |
| SCHEMBL22690652 | 0.85 | KMT2A (0.36) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL22690653 | 0.85 | KMT2A (0.36) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL28786949 | 0.79 | MMP9 (0.41) | KMT2ALPAR3 | |
| SCHEMBL16124694 | 0.77 | EPHX2 (0.60) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL7218627 | 0.76 | EPHX2 (0.67) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL7218630 | 0.76 | EPHX2 (0.67) | CA2CA4EPHX2NOD1KMT2A | |
| SCHEMBL2383184 | 0.75 | PPARD (0.54) | KMT2APPARD | |
| SCHEMBL20552606 | 0.74 | EPHX2 (0.65) | CA2CA4EPHX2NOD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136076-A | MCL-1 inhibitor antibody drug conjugates and methods of use | 诺华股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114728077-A | MCL-1 inhibitor antibody-drug conjugates and methods of use | 诺华股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728076-A | MCL-1 inhibitor antibody-drug conjugates and methods of use | 诺华股份有限公司 | 2022-07-08 | — | — | CN | disclosed |