Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299064 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL2246884 | 0.84 | DPP4 (0.47) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL20175446 | 0.84 | NOS1 (0.44) | KDM4EALDH1A1GLAMAPTRAB9A | |
| SCHEMBL10630430 | 0.83 | ALDH1A1 (0.42) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL13146542 | 0.80 | ALDH1A1 (0.45) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL10630396 | 0.80 | KDM4E (0.41) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL13146570 | 0.80 | ALDH1A1 (0.45) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL16785692 | 0.80 | DPP4 (0.53) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL498537 | 0.80 | DPP4 (0.53) | DPP4KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL14437828 | 0.80 | DPP4 (0.53) | DPP4KDM4EALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |