Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884721 | 0.91 | MMP2 (0.43) | MMP2MMP9HRH2HRH1MEN1 | |
| SCHEMBL2228850 | 0.87 | GRIN2B (0.46) | MMP2MMP9GRIN2BHRH2HRH1 | |
| SCHEMBL13837204 | 0.85 | GRIN2B (0.43) | MMP2MMP9GRIN2BHRH2HRH1 | |
| SCHEMBL2362512 | 0.81 | MMP2 (0.43) | MMP2MMP9GRIN2BPOLBMEN1 | |
| SCHEMBL28064182 | 0.80 | LTA4H (0.36) | POLBMAPTSMN1; SMN2LTA4HKCNA5 | |
| SCHEMBL2365458 | 0.78 | LIPE (0.43) | MMP2MMP9GRIN2BSMN1; SMN2 | |
| SCHEMBL2229112 | 0.78 | GRM5 (0.43) | MMP2MMP9HRH2HRH1MEN1 | |
| SCHEMBL2226384 | 0.76 | HRH3 (0.43) | MMP2MMP9GRIN2BHRH2HRH1 | |
| SCHEMBL2228891 | 0.76 | TEAD1 (0.50) | MMP2MMP9GRIN2BGAAMAPT | |
| SCHEMBL2231117 | 0.76 | TEAD1 (0.47) | MMP2MMP9GRIN2BHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-A | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SANOFI AVENTIS | 2012-11-28 | — | — | CN | disclosed |