Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.50 |
| ▸ | PREP | P48147 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946627 | 1.00 | SIGMAR1 (0.50) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL31427469 | 0.87 | SIGMAR1 (0.45) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946632 | 0.82 | PREP (0.51) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946630 | 0.82 | PREP (0.51) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946597 | 0.82 | PREP (0.53) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946599 | 0.82 | PREP (0.53) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946573 | 0.82 | TSHR (0.54) | SIGMAR1TMEM97PREPACE2AADAT | |
| SCHEMBL28946605 | 0.81 | RIPK1 (0.46) | PREP | |
| SCHEMBL28946625 | 0.81 | RIPK1 (0.46) | PREP | |
| SCHEMBL28526231 | 0.81 | RIPK1 (0.44) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490708-A | Sulfonamide macrocyclic derivatives, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2022-12-20 | — | — | CN | disclosed |