Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16934082 | 0.82 | TSHR (0.43) | BRD4HTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1192568 | 0.80 | — | — | |
| SCHEMBL946983 | 0.80 | TSHR (0.45) | BRD4HTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8819360 | 0.78 | P2RX7 (0.46) | TSHRPLA2G7P2RX7HSD11B1IDO1 | |
| SCHEMBL5890645 | 0.78 | TSHR (0.39) | BRD4HTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27565196 | 0.77 | NPC1 (0.38) | BRD4HTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6251653 | 0.75 | ATM (0.46) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL30395630 | 0.75 | ATM (0.46) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL3179746 | 0.75 | TSHR (0.45) | BRD4HTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10715263 | 0.74 | CYP2A6 (0.43) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890987-A | Thiophenol-thiophene ligand and preparation method thereof, olefin polymerization catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-12 | — | — | CN | disclosed |