Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946983 | 0.83 | TSHR (0.45) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15259433 | 0.82 | TRPA1 (0.39) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL284410 | 0.80 | TSHR (0.47) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27565196 | 0.80 | NPC1 (0.38) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28947604 | 0.78 | BRD4 (0.38) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3179746 | 0.78 | TSHR (0.45) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9701669 | 0.78 | TSHR (0.45) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30548743 | 0.78 | — | — | |
| SCHEMBL21520 | 0.78 | — | — | |
| SCHEMBL23891346 | 0.77 | CA12 (0.50) | TSHRACHENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1380572-A1 | POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | TMT1A, MSMO1, TST | TSHR 1397/4885ACHE 3828/4885NPC1 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.