Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 7/20 | 0.55 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL289481 | 0.84 | SMARCA2 (0.56) | SMARCA2SMARCA4CYP3A4CYP3A5CNR1 | |
| SCHEMBL119685 | 0.80 | SMARCA2 (0.79) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| Phenylurea SCHEMBL8780484 | 0.74 | SMARCA2 (0.68) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| Diphenylamine SCHEMBL27844403 | 0.73 | CDK2 (0.59) | CYP3A4MEN1KMT2A | |
| SCHEMBL22125200 | 0.73 | SMARCA2 (1.00) | SMARCA2SMARCA4TAAR1MEN1KMT2A | |
| SCHEMBL9599834 | 0.73 | SMARCA2 (0.86) | SMARCA2SMARCA4CNR1MEN1KMT2A | |
| Benzoic Acid SCHEMBL28391615 | 0.71 | BRD4 (0.45) | — | |
| Nitric Acid SCHEMBL28189380 | 0.71 | SMARCA2 (0.63) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| Purine SCHEMBL29465224 | 0.70 | ALDH1A1 (0.39) | CYP3A4 | |
| Purine SCHEMBL28164598 | 0.70 | ALDH1A1 (0.44) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120137390-A1 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN INC. | 2012-05-31 | — | — | US | disclosed |
| EP-2427047-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ArborGen Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129737-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN, LLC (US) | 2010-11-11 | — | — | WO | disclosed |