Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.56 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL289483 | 0.84 | SMARCA2 (0.55) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| SCHEMBL119685 | 0.81 | SMARCA2 (0.79) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| Phenylurea SCHEMBL8780484 | 0.77 | SMARCA2 (0.68) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| SCHEMBL22125200 | 0.74 | SMARCA2 (1.00) | SMARCA2SMARCA4TAAR1MEN1KMT2A | |
| SCHEMBL9599834 | 0.74 | SMARCA2 (0.86) | SMARCA2SMARCA4CNR1MEN1KMT2A | |
| Nitric Acid SCHEMBL28189380 | 0.72 | SMARCA2 (0.63) | SMARCA2SMARCA4CNR1TAAR1MEN1 | |
| SCHEMBL22154745 | 0.71 | DDX3X (0.68) | SMARCA2SMARCA4MEN1KMT2AKDR | |
| SCHEMBL22125215 | 0.70 | SMARCA2 (0.69) | SMARCA2SMARCA4CNR1 | |
| SCHEMBL9410880 | 0.70 | MEN1 (0.72) | SMARCA2SMARCA4MEN1KMT2AKDR | |
| SCHEMBL11047103 | 0.70 | SMARCA2 (0.79) | SMARCA2SMARCA4CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120137390-A1 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN INC. | 2012-05-31 | — | — | US | disclosed |
| EP-2427047-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ArborGen Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129737-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN, LLC (US) | 2010-11-11 | — | — | WO | disclosed |