Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30219706 | 1.00 | CYP2D6 (0.54) | CYP2D6HTR1AHTR2AHTR2CDRD3 | |
| SCHEMBL28948318 | 0.84 | NQO2 (0.51) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL30219711 | 0.82 | MAPT (0.50) | HTR2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL28948347 | 0.82 | MAPT (0.50) | HTR2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8177728 | 0.81 | KMO (0.55) | ALDH1A1TP53SMN1; SMN2MAPTHPGD | |
| SCHEMBL8799955 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TP53SMN1; SMN2MAPTHPGD | |
| SCHEMBL28948374 | 0.77 | KMO (0.51) | ALDH1A1TP53SMN1; SMN2MAPTHPGD | |
| SCHEMBL28948365 | 0.77 | KMT2A (0.53) | ALDH1A1SMN1; SMN2MAPTRAB9AHTR2B | |
| SCHEMBL8798062 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL28948346 | 0.74 | MAPT (0.49) | DRD3ALDH1A1SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677610-A | Benzoxazolinone derivatives, preparation method and application thereof | 安徽中医药大学 | 2023-02-03 | — | — | CN | claimed |
| CN-115677610-A | Benzoxazolinone derivatives, preparation method and application thereof | 安徽中医药大学 | 2023-02-03 | — | — | CN | disclosed |