Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799955 | 0.87 | ALDH1A1 (0.53) | KMOMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL28948374 | 0.86 | KMO (0.51) | KMOMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL8798062 | 0.83 | ALDH1A1 (0.55) | KMOMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL28948318 | 0.82 | NQO2 (0.51) | KMOMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL28948346 | 0.82 | MAPT (0.49) | KMOALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30219706 | 0.81 | CYP2D6 (0.54) | ALDH1A1LMNAMAPTTP53HPGD | |
| SCHEMBL28948321 | 0.81 | CYP2D6 (0.54) | ALDH1A1LMNAMAPTTP53HPGD | |
| SCHEMBL28948365 | 0.81 | KMT2A (0.53) | KMOALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28948358 | 0.80 | MAOA (0.52) | KMOALDH1A1LMNAMAPTHPGD | |
| SCHEMBL28948363 | 0.80 | MAPT (0.47) | KMOALDH1A1LMNAMETMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309823-A1 | PERCUTANEOUS ABSORPTION PREPARATIONS | SUZUKI YASUYUKI (JP) | 2012-12-06 | — | — | US | disclosed |
| US-20090264521-A1 | Percutaneous absorption preparation | SUZUKI YASUYUKI | 2009-10-22 | — | — | US | disclosed |
| WO-2008083204-A2 | MODULATION OF NEUROGENESIS BY MELATONINERGIC LIGANDS | BRAINCELLS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264521-A1 | Percutaneous absorption preparation | MTNR1A, MTNR1B, NPSR1 | KMO 242/4885MTNR1A 1/4885MTNR1B 2/4885 |
| US-20120309823-A1 | PERCUTANEOUS ABSORPTION PREPARATIONS | MTNR1A, MTNR1B, MC1R | KMO 254/4885MTNR1A 1/4885MTNR1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.