Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617063 | 0.90 | FAAH (0.48) | TLR7TLR8GAAHTTTOP2A | |
| SCHEMBL1960247 | 0.89 | TLR7 (0.47) | TLR7TLR8GAAHTTPDE4A | |
| SCHEMBL4158992 | 0.86 | TNF (0.48) | TLR7GAATOP2ALMNASMN1; SMN2 | |
| SCHEMBL4147393 | 0.85 | FAAH (0.48) | TLR7GAATOP2ASMN1; SMN2CNR1 | |
| SCHEMBL4165503 | 0.85 | TLR7 (0.49) | TLR7TLR8GAAHTTPDE4A | |
| SCHEMBL4138665 | 0.84 | FAAH (0.50) | TLR7TOP2ASMN1; SMN2 | |
| SCHEMBL4011233 | 0.84 | FAAH (0.50) | TLR7TOP2ASMN1; SMN2 | |
| SCHEMBL5616965 | 0.84 | TLR7 (0.52) | TLR7TLR8GAAHTTPDE4A | |
| SCHEMBL5616925 | 0.83 | TLR7 (0.48) | TLR7 | |
| SCHEMBL2897450 | 0.83 | TLR7 (0.43) | TLR7TLR8GAAHTTTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225555-A1 | Imidazoquinolines with Immuno-Modulating Properties | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-8436178-B2 | Imidazoquinolines with immuno-modulating properties | ASTRAZENECA AB (SE) | 2013-05-07 | — | — | US | disclosed |
| EP-2155743-B1 | IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES | ASTRAZENECA AB (SE) | 2012-08-29 | — | — | EP | disclosed |
| US-20100280001-A1 | IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280001-A1 | IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES | IFNG, FCGRT, IFNAR1 | TLR7 267/4885TLR8 1392/4885GAA 4117/4885 |
| US-20130225555-A1 | Imidazoquinolines with Immuno-Modulating Properties | IFNG, FCGRT, IFNAR1 | TLR7 267/4885TLR8 1392/4885GAA 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.