Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320111 | 0.76 | HTR6 (0.58) | CA1CA2CA9KMT2AHTR6 | |
| SCHEMBL23300923 | 0.76 | HTR6 (0.58) | CA1CA2CA9KMT2AHTR6 | |
| SCHEMBL29839433 | 0.76 | HTR6 (0.58) | CA1CA2CA9KMT2AHTR6 | |
| SCHEMBL23301003 | 0.76 | HTR6 (0.58) | CA1CA2CA9KMT2AHTR6 | |
| SCHEMBL7029967 | 0.74 | KMT2A (0.52) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL29728552 | 0.74 | KMT2A (0.52) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL10730924 | 0.74 | HTR6 (0.49) | MEN1KMT2AHTR6KDM4ESMN1; SMN2 | |
| SCHEMBL3952526 | 0.71 | CA1 (0.59) | CA1CA2CA9KMT2APRSS1 | |
| SCHEMBL473212 | 0.70 | ATM (0.47) | MEN1KMT2AIRAK4LMNASMN1; SMN2 | |
| SCHEMBL26566772 | 0.70 | PTGS2 (0.57) | MEN1KMT2ACYP1A2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697993-A | Pyrimidines as AXL inhibitors | 南京正大天晴制药有限公司 | 2023-02-03 | — | — | CN | disclosed |