Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952017 | 1.00 | CTSK (0.50) | CTSKCTSSEPHX1ITGAVITGB6 | |
| SCHEMBL28951196 | 0.90 | CTSK (0.47) | CTSKCTSSEPHX1ITGAVITGB6 | |
| SCHEMBL25524311 | 0.90 | CTSK (0.47) | CTSKCTSSEPHX1ITGAVITGB6 | |
| SCHEMBL21571163 | 0.85 | CTSS (0.54) | CTSKCTSSEPHX1HPGDYAP1 | |
| SCHEMBL2748421 | 0.85 | CTSS (0.54) | CTSKCTSSEPHX1HPGDYAP1 | |
| SCHEMBL6689450 | 0.85 | CTSS (0.54) | CTSKCTSSEPHX1HPGDYAP1 | |
| SCHEMBL6879172 | 0.84 | CTSS (0.49) | CTSKCTSSEPHX1HPGDYAP1 | |
| SCHEMBL6592042 | 0.84 | CTSS (0.49) | CTSKCTSSEPHX1HPGDYAP1 | |
| SCHEMBL25198479 | 0.83 | MAPK1 (0.53) | CTSKCTSSITGAVITGB6MAPK1 | |
| SCHEMBL25266611 | 0.83 | MAPK1 (0.53) | CTSKCTSSITGAVITGB6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |