Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592042 | 1.00 | CTSS (0.49) | CTSSCTSKEPHX1YAP1HPGD | |
| Lithium Ion SCHEMBL5528977 | 0.88 | CTSS (0.47) | CTSSCTSKEPHX1HPGDEPHX2 | |
| SCHEMBL6876113 | 0.85 | ALDH1A1 (0.50) | CTSSHPGDCTSLGRNSORT1 | |
| SCHEMBL28952015 | 0.84 | CTSK (0.50) | CTSSCTSKEPHX1YAP1HPGD | |
| SCHEMBL28952017 | 0.84 | CTSK (0.50) | CTSSCTSKEPHX1YAP1HPGD | |
| SCHEMBL6874696 | 0.82 | CPB2 (0.55) | CTSSCTSKCTSLGRNSORT1 | |
| SCHEMBL2748421 | 0.81 | CTSS (0.54) | CTSSCTSKEPHX1YAP1HPGD | |
| SCHEMBL21571163 | 0.81 | CTSS (0.54) | CTSSCTSKEPHX1YAP1HPGD | |
| SCHEMBL6689450 | 0.81 | CTSS (0.54) | CTSSCTSKEPHX1YAP1HPGD | |
| SCHEMBL21427220 | 0.79 | CTSK (0.70) | CTSSCTSKEPHX1CTSLGRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |