Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952133 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28964714 | 0.92 | PTGS2 (0.39) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28964715 | 0.92 | PTGS2 (0.39) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28951954 | 0.91 | MAPT (0.40) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28951951 | 0.91 | MAPT (0.40) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28952164 | 0.90 | SUV39H2 (0.40) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28952161 | 0.90 | MAP1LC3B (0.46) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28952165 | 0.90 | SUV39H2 (0.40) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28952134 | 0.89 | NPSR1 (0.44) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL28952127 | 0.89 | NPSR1 (0.44) | KDM4EALDH1A1HPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703755-B | 2H-benzopyran-2-one derivatives and uses thereof | 成都赜灵生物医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115703755-A | 2H-benzopyran-2-one derivatives and uses thereof | 成都赜灵生物医药科技有限公司 | 2023-02-17 | — | — | CN | disclosed |