Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964714 | 1.00 | PTGS2 (0.39) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28951954 | 0.94 | MAPT (0.40) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28951951 | 0.94 | MAPT (0.40) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28952164 | 0.93 | SUV39H2 (0.40) | PTGS2MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28952165 | 0.93 | SUV39H2 (0.40) | PTGS2MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28952136 | 0.92 | KDM4E (0.42) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28952133 | 0.92 | KDM4E (0.42) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL30275987 | 0.88 | CTSS (0.40) | PTGS2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28951969 | 0.88 | MAPT (0.39) | PTGS2MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28951966 | 0.88 | MAPT (0.39) | PTGS2MAPTSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703755-B | 2H-benzopyran-2-one derivatives and uses thereof | 成都赜灵生物医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115703755-A | 2H-benzopyran-2-one derivatives and uses thereof | 成都赜灵生物医药科技有限公司 | 2023-02-17 | — | — | CN | disclosed |