Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 10/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30259600 | 1.00 | SRC (0.37) | SRCHTR6PTGDRPTGDR2HTR1A | |
| SCHEMBL28952982 | 0.74 | — | — | |
| SCHEMBL28952988 | 0.72 | HTR6 (0.41) | SRCHTR6PTGDRPTGDR2 | |
| SCHEMBL26377978 | 0.69 | CCR5 (0.39) | SRCHTR6PSEN1PSEN2APH1B | |
| SCHEMBL2399724 | 0.69 | NCEH1 (0.49) | — | |
| SCHEMBL29208197 | 0.69 | SRC (0.39) | SRCHTR6PTGDRPTGDR2 | |
| SCHEMBL4315339 | 0.69 | HTR6 (0.49) | HTR6HTR1ADRD2 | |
| SCHEMBL23156279 | 0.69 | HTR6 (0.37) | SRCHTR6PTGDRPTGDR2PSEN1 | |
| SCHEMBL31279562 | 0.69 | CCR5 (0.38) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19252346 | 0.69 | CCR5 (0.38) | HTR6PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677722-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2023-02-03 | — | — | CN | disclosed |