Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144383 | 0.82 | HTR6 (0.48) | HTR6SRCCXCL8NOD1MEN1 | |
| SCHEMBL29208197 | 0.81 | SRC (0.39) | HTR6SRCPTGDRPTGDR2 | |
| SCHEMBL31304851 | 0.79 | HTR6 (0.44) | HTR6SRCCXCL8NOD1CA12 | |
| SCHEMBL17422770 | 0.73 | HTR6 (0.42) | HTR6SRCCXCL8NOD1MEN1 | |
| SCHEMBL28952979 | 0.73 | CXCL8 (0.46) | HTR6SRCCXCL8NOD1MEN1 | |
| SCHEMBL19268777 | 0.73 | SRC (0.44) | HTR6SRCCXCL8NOD1PTGDR | |
| SCHEMBL30259600 | 0.72 | SRC (0.37) | HTR6SRCPTGDRPTGDR2 | |
| SCHEMBL28952976 | 0.72 | SRC (0.37) | HTR6SRCPTGDRPTGDR2 | |
| SCHEMBL2088346 | 0.71 | MTNR1B (0.45) | HTR6SRCNOD1MEN1MAPT | |
| SCHEMBL17422830 | 0.70 | LMNA (0.42) | HTR6SRCCXCL8NOD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677722-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2023-02-03 | — | — | CN | disclosed |