Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051613 | 0.89 | PAX8 (0.65) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL29631623 | 0.89 | PAX8 (0.65) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL8342118 | 0.89 | PAX8 (0.65) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL29692738 | 0.83 | PAX8 (1.00) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL1164645 | 0.83 | PAX8 (1.00) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL1164644 | 0.83 | PAX8 (1.00) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL30197879 | 0.81 | PAX8 (0.60) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL17560758 | 0.81 | PAX8 (0.59) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL17560762 | 0.81 | PAX8 (0.59) | PAX8KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL19456444 | 0.80 | PAX8 (0.66) | PAX8KDM4EHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677737-A | Rare earth complex with potential anti-tumor effect and preparation method thereof | 沈阳化工大学 | 2023-02-03 | — | — | CN | disclosed |