SCHEMBL8342118

SCHEMBL8342118

C(=N/Nc1ccccn1)\c1ccccn1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.65
RAB9A P51151 9/20 0.61
NPC1 O15118 7/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
LMNA P02545 4/20 0.61
GAA P10253 4/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
MAPT P10636 3/20 0.61
MAPK1 P28482 1/20 0.61
CASP3 P42574 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
KDM4E B2RXH2 2/20 0.58
PKM P14618 2/20 0.58
HTT P42858 2/20 0.58
MITF O75030 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
KMT2A Q03164 5/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5051613 1.00 PAX8 (0.65) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL29631623 1.00 PAX8 (0.65) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL28952987 0.89 PAX8 (0.70) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL30197879 0.84 PAX8 (0.60) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL28170008 0.83 PAX8 (0.58) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL6714490 0.82 RAB9A (0.55) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL9735307 0.82 GAA (0.64) RAB9ANPC1SMN1; SMN2LMNAGAA
SCHEMBL9735520 0.82 RAB9A (0.58) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL28643368 0.82 RAB9A (0.58) PAX8RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL6714484 0.82 RAB9A (0.55) PAX8RAB9ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250153-A A kind of preparation method of trans- disubstituted alkene 青岛科技大学 2018-07-06 CN claimed
US-4681828-A Method of chemical electrographic image amplification using chemically active toner particles EASTMAN KODAK COMPANY (US) 1987-07-21 US claimed
WO-2024048435-A1 RESIN COMPOSITION, CURED ARTICLE, LAMINATE, METHOD FOR PRODUCING CURED ARTICLE, METHOD FOR PRODUCING LAMINATE, METHOD FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE 富士フイルム株式会社 2024-03-07 WO disclosed
CN-108250153-A A kind of preparation method of trans- disubstituted alkene 青岛科技大学 2018-07-06 CN disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-4681828-A Method of chemical electrographic image amplification using chemically active toner particles EASTMAN KODAK COMPANY (US) 1987-07-21 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed