Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | HTT | P42858 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342118 | 0.84 | PAX8 (0.65) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL5051613 | 0.84 | PAX8 (0.65) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL29631623 | 0.84 | PAX8 (0.65) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL17560758 | 0.83 | PAX8 (0.59) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL17560762 | 0.83 | PAX8 (0.59) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL28952987 | 0.81 | PAX8 (0.70) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL28170008 | 0.79 | PAX8 (0.58) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL3079735 | 0.77 | KDM4E (0.58) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL6711432 | 0.77 | KDM4E (0.58) | PAX8KDM4EHTTMAPTKMT2A | |
| SCHEMBL1164645 | 0.75 | PAX8 (1.00) | PAX8KDM4EHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566012-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD (AU) | 2023-01-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566012-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | PAX8 4267/4885KDM4E 3521/4885HTT 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.