SCHEMBL28953262

SCHEMBL28953262

CC(C)N1C(=O)c2ccccc2C1(C)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PGR P06401 8/20 0.42
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MDM2 Q00987 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21347391 0.87 ALDH1A1 (0.49) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL23707030 0.81 PGR (0.45) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL17751369 0.78 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL28242050 0.76 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL2598812 0.71 ALDH1A1 (0.42) ALDH1A1PGRMDM2
SCHEMBL29031894 0.70 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL6589296 0.69 RXFP1 (0.66) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL28843431 0.69 KDM4E (0.57) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL1948836 0.66 PGR (0.47) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL29155436 0.66 RXFP1 (0.55) ALDH1A1MEN1KMT2APGRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108964-A Phthalide derivative, preparation method and application 成都陈泷张科技有限责任公司 2022-09-27 CN disclosed