Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28243153 | 0.80 | PGR (0.45) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL21663065 | 0.79 | KDM4E (0.34) | PGRALDH1A1MEN1KMT2ATTR | |
| SCHEMBL28249000 | 0.78 | PGR (0.46) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL13136409 | 0.77 | MDM2 (0.44) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL23707030 | 0.76 | PGR (0.45) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL30372076 | 0.76 | HRH3 (0.51) | PGRALDH1A1MEN1KMT2ACASP3 | |
| SCHEMBL30056810 | 0.76 | MDM2 (0.57) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL26327450 | 0.75 | KMT2A (0.42) | PGRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12549140 | 0.75 | CA1 (0.39) | PGRALDH1A1MEN1KMT2AMDM2 | |
| SCHEMBL20672234 | 0.75 | CA1 (0.39) | MEN1KMT2AMDM2CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | claimed |
| WO-2023220541-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | MERCK PATENT GMBH (DE) | 2023-11-16 | — | — | WO | disclosed |
| US-20230350294-A1 | Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20230350294-A1 | Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2023-06-15 | — | — | US | disclosed |
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022222951-A1 | AROMATIC CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-114516856-A | Dihydroisoquinolinone and isoindolinone derivatives and uses thereof | 中国科学院合肥物质科学研究院 | 2022-05-20 | — | — | CN | disclosed |
| US-8106135-B2 | Polyethersulfone compositions with high heat and good impact resistance | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-01-31 | — | — | US | disclosed |
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2011-06-09 | — | — | US | disclosed |
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2011-06-09 | — | — | US | disclosed |
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2011-06-09 | — | — | US | disclosed |
| EP-2168966-A1 | BICYCLOANILINE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168966-A1 | BICYCLOANILINE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-20090182079-A1 | Carbon Black Surface-Modified with Benzene Compound and Carbon Black Dispersion Composition for Black Matrix Using the Same | CHEIL INDUSTRIES INC. (KR) | 2009-07-16 | — | — | US | disclosed |
| US-20090182079-A1 | Carbon Black Surface-Modified with Benzene Compound and Carbon Black Dispersion Composition for Black Matrix Using the Same | CHEIL INDUSTRIES INC. (KR) | 2009-07-16 | — | — | US | disclosed |
| US-20070049724-A1 | POLYETHERSULFONE COMPOSITIONS WITH HIGH HEAT AND GOOD IMPACT RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 2007-03-01 | — | — | US | disclosed |
| US-20070031514-A1 | Use of isoindolinone derivatives as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031514-A1 | Use of isoindolinone derivatives as insecticides | DDT, CYP1A2, CYP1A1 | PGR 4598/4885ALDH1A1 47/4885MEN1 2430/4885 |
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | WEE1, WEE2, CCNK | PGR 2827/4885ALDH1A1 1894/4885MEN1 606/4885 |
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | PGR 935/4885ALDH1A1 2968/4885MEN1 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.