Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | WEE1 | P30291 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910563 | 0.91 | SLC2A1 (0.48) | PKMYT1SYKSLC2A1KDRWEE1 | |
| SCHEMBL28531544 | 0.88 | PLK1 (0.51) | PKMYT1SYKSLC2A1PLK1WEE1 | |
| SCHEMBL21596382 | 0.86 | EGFR (0.51) | JAK3JAK2BTKEGFRITK | |
| SCHEMBL28546937 | 0.84 | JAK3 (0.47) | PKMYT1JAK3JAK2LRRK2 | |
| SCHEMBL28953581 | 0.81 | SYK (0.49) | PKMYT1SYKSLC2A1KDRWEE1 | |
| SCHEMBL28953583 | 0.78 | EGFR (0.49) | PKMYT1SLC2A1PLK1WEE1ALK | |
| SCHEMBL21600934 | 0.77 | EGFR (0.49) | KDRWEE1ALKJAK3AURKA | |
| SCHEMBL21600797 | 0.75 | EGFR (0.51) | PLK1JAK3JAK2IGF1REGFR | |
| SCHEMBL28525616 | 0.75 | WEE1 (0.57) | PKMYT1SYKSLC2A1PLK1KDR | |
| SCHEMBL30379743 | 0.73 | WEE1 (0.53) | PKMYT1SYKSLC2A1KDRWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |