Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.45 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531544 | 0.91 | PLK1 (0.51) | EGFRALKPLK1SLC2A1PKMYT1 | |
| SCHEMBL28531632 | 0.89 | FGFR1 (0.47) | EGFRALKPLK1SLC2A1WEE1 | |
| SCHEMBL28910563 | 0.87 | SLC2A1 (0.48) | ALKSLC2A1PKMYT1WEE1FGFR1 | |
| SCHEMBL21600822 | 0.85 | EGFR (0.49) | EGFRPLK1INSRIGF1RMAPK3 | |
| SCHEMBL28953570 | 0.78 | PKMYT1 (0.49) | EGFRALKPLK1SLC2A1PKMYT1 | |
| SCHEMBL21600797 | 0.77 | EGFR (0.51) | EGFRPLK1INSRIGF1RMAPK3 | |
| SCHEMBL28953581 | 0.76 | SYK (0.49) | ALKSLC2A1PKMYT1WEE1FGFR1 | |
| SCHEMBL21600796 | 0.75 | EGFR (0.52) | EGFRPLK1INSRIGF1RMAPK3 | |
| SCHEMBL28546192 | 0.75 | PLK1 (0.57) | EGFRALKPLK1FGFR1FGFR2 | |
| SCHEMBL28540649 | 0.75 | SLC2A1 (0.66) | EGFRALKPLK1SLC2A1PKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |