Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.65 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.65 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | ACR | P10323 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058586 | 0.92 | CA2 (0.55) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL12766491 | 0.92 | CA2 (0.55) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL14096160 | 0.92 | CA2 (0.55) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL14095919 | 0.88 | MMP3 (0.59) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL5945234 | 0.88 | MMP3 (0.59) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL13041595 | 0.88 | MMP3 (0.59) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL29038955 | 0.86 | ALDH1A1 (0.58) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL8496209 | 0.86 | ALDH1A1 (0.58) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL16493483 | 0.80 | ALDH1A1 (0.56) | PARP10PARP15PARP2ALDH1A1CYP1A2 | |
| SCHEMBL17527511 | 0.80 | PRSS1 (0.50) | PARP10PARP15PARP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066728-B1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-07-28 | — | — | EP | disclosed |
| US-7709562-B2 | Low temperature ductility, flowability; cyanophenol endcapped polycarbonate, impact modifier and flame retardant; extrusion molding materials | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-04 | — | — | US | disclosed |
| US-7652083-B2 | Thermoplastic compostions, methods of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-01-26 | — | — | US | disclosed |
| EP-2137232-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | Sabic Innovative Plastics IP BV (US) | 2009-12-30 | — | — | EP | disclosed |
| EP-2066728-A2 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | Sabic Innovative Plastics IP B.V. (NL) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008060714-A9 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008127424-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP BV (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008060714-A2 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-22 | — | — | WO | disclosed |
| US-20080081855-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-04-03 | — | — | US | disclosed |
| US-20080081860-A1 | Low temperature ductility, flowability; cyanophenol endcapped polycarbonate, impact modifier and flame retardant; extrusion molding materials | SABIC INNOVATIVE PLASTICS IP BV (US) | 2008-04-03 | — | — | US | disclosed |
| US-20080081892-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-04-03 | — | — | US | disclosed |