Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25010024 | 0.89 | CDC7 (0.58) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL28809840 | 0.89 | CDC7 (0.58) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL20497362 | 0.87 | CDC7 (0.56) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL2895624 | 0.85 | CDC7 (0.54) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL18381687 | 0.85 | CDC7 (0.54) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL17086049 | 0.85 | CDC7 (0.54) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL28633144 | 0.85 | HDAC1 (0.58) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL2897806 | 0.82 | CDC7 (0.70) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL27953889 | 0.82 | CDC7 (0.52) | CDC7P2RX7HDAC1HDAC3HDAC2 | |
| SCHEMBL2896191 | 0.82 | HDAC1 (0.51) | CDC7P2RX7HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640880-A | The synthetic method of 1- alkyl -5- aryl -1,2,3- triazole compounds | 河南师范大学 | 2018-10-12 | — | — | CN | claimed |
| EP-1306131-B1 | Cross-coupling process using a catalyst comprising a cyclic nitrogen ligand | SUMITOMO CHEMICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-9447246-B2 | Method of covalently bonding an organic metal complex to a polymer | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9447246-B2 | Method of covalently bonding an organic metal complex to a polymer | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9447245-B2 | Cross-linking and stabilization of organic metal complexes in networks | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9447245-B2 | Cross-linking and stabilization of organic metal complexes in networks | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| EP-2729505-B1 | METHOD FOR COVALENT BINDING OF A METAL COMPOUND TO A POLYMER | CYNORA GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-20150259305-A1 | CATALYTIC REACTION | NATIONAL TSING HUA UNIVERSITY (TW) | 2015-09-17 | — | — | US | disclosed |
| US-20150259305-A1 | CATALYTIC REACTION | NATIONAL TSING HUA UNIVERSITY (TW) | 2015-09-17 | — | — | US | disclosed |
| EP-1943004-B1 | RUTHENIUM-CATALYZED CYCLOADDITION OF ALKYNES AND ORGANIC AZIDES | SCRIPPS RESEARCH INST (US) | 2015-06-03 | — | — | EP | disclosed |
| WO-2013007709-A2 | CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS | CYNORA GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |
| US-20100286405-A1 | Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-11 | — | — | US | disclosed |
| US-20100286405-A1 | Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-11 | — | — | US | disclosed |
| CN-101316640-A | Ruthenium-catalyzed cycloaddition of alkynes and organic azides | SCRIPPS RESEARCH INST (US) | 2008-12-03 | — | — | CN | disclosed |
| EP-1943004-A2 | RUTHENIUM-CATALYZED CYCLOADDITION OF ALKYNES AND ORGANIC AZIDES | The Scripps Research Institute (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007041451-A2 | RUTHENIUM-CATALYZED CYCLOADDITION OF ALKYNES AND ORGANIC AZIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20060111593-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-05-25 | — | — | US | disclosed |
| US-7041856-B2 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | CDC7 3696/4885P2RX7 1712/4885HDAC1 772/4885 |
| US-20100286405-A1 | Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides | CBR3, AOC3, CYB5R3 | CDC7 1557/4885P2RX7 1252/4885HDAC1 2070/4885 |
| US-20150259305-A1 | CATALYTIC REACTION | HAO2, CAT, HAAO | CDC7 458/4885P2RX7 4161/4885HDAC1 2575/4885 |
| US-20060111593-A1 | Coupling catalyst and process using the same | RPL22, C9, RBM22 | CDC7 3395/4885P2RX7 332/4885HDAC1 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.