Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYD88 | Q99836 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205153 | 0.83 | MYD88 (0.86) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL28954886 | 0.80 | MYD88 (0.60) | MYD88MEN1KMT2ASLC22A12ALDH1A1 | |
| SCHEMBL28954767 | 0.78 | MYD88 (1.00) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL30205183 | 0.76 | MYD88 (0.80) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL28954891 | 0.76 | MYD88 (0.85) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL30585260 | 0.73 | TSHR (0.53) | MYD88MEN1KMT2ASLC22A12ALDH1A1 | |
| SCHEMBL15544374 | 0.73 | MEN1 (0.62) | MYD88MEN1KMT2ASLC22A12ALDH1A1 | |
| SCHEMBL29078406 | 0.72 | MYD88 (0.68) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL29078361 | 0.71 | MYD88 (0.55) | MYD88MEN1KMT2AALDH1A1HTT | |
| SCHEMBL20804834 | 0.68 | DRD4 (0.56) | ALDH1A1HTTLMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | disclosed |