Phosphoric Acid

Phosphoric Acid

SCHEMBL28954909

CC(C)(C)c1cccc(C(C)(C)C)c1.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.48

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.48
HDAC4 P56524 1/20 0.48
HDAC2 Q92769 1/20 0.48
ACHE P22303 3/20 0.44
KIF11 P52732 1/20 0.42
PGK1 P00558 2/20 0.42
PGK2 P07205 2/20 0.42
RXRA P19793 2/20 0.42
RXRB P28702 2/20 0.42
HDAC6 Q9UBN7 2/20 0.41
HDAC3 O15379 1/20 0.41
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
PLA2G1B P04054 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27558416 0.88 HDAC8 (0.43) HDAC8HDAC4HDAC2ACHEKIF11
Phosphoric Acid SCHEMBL27535905 0.85 KIF11 (0.44) HDAC8HDAC4HDAC2ACHEKIF11
Tert-Butylbenzene SCHEMBL29482748 0.84 RAB9A (0.42) PTPN1ALDH1A1NPC1RAB9AL3MBTL1
Phosphoric Acid SCHEMBL6285652 0.84 HDAC8 (0.55) HDAC8HDAC4HDAC2ACHEKIF11
Tert-Butylbenzene SCHEMBL27470416 0.84 RAB9A (0.42) PTPN1ALDH1A1NPC1RAB9AL3MBTL1
Phosphoric Acid SCHEMBL21327914 0.84 HDAC8 (0.55) HDAC8HDAC4HDAC2ACHEKIF11
Phosphoric Acid SCHEMBL28929945 0.84 HDAC8 (0.55) HDAC8HDAC4HDAC2ACHEKIF11
Phosphoric Acid SCHEMBL29023601 0.84 HDAC8 (0.55) HDAC8HDAC4HDAC2ACHEKIF11
Phosphoric Acid SCHEMBL27558610 0.84 HDAC8 (0.43) HDAC8HDAC4HDAC2ACHEKIF11
SCHEMBL129151 0.83 HDAC8 (0.56) HDAC8HDAC4HDAC2ACHEKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710381-A Polypropylene composite additive and application thereof 呈和科技股份有限公司 2023-02-24 CN disclosed
CN-115710381-A Polypropylene composite additive and application thereof 呈和科技股份有限公司 2023-02-24 CN disclosed