Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 4/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856487 | 0.86 | GRM2 (0.31) | — | |
| SCHEMBL28856553 | 0.86 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28856479 | 0.86 | MAPT (0.34) | MAPTALDH1A1MAPK1KDM4ECYP1A2 | |
| SCHEMBL28856551 | 0.85 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28856504 | 0.85 | SLC22A12 (0.33) | SLC22A12CYP1A2 | |
| SCHEMBL28856517 | 0.83 | SLC22A12 (0.43) | SLC22A12 | |
| SCHEMBL28856496 | 0.81 | CA12 (0.39) | SLC22A12MAPTLMNAMAPK1KMT2A | |
| SCHEMBL28856516 | 0.79 | KDM4E (0.33) | SLC22A12ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28856521 | 0.78 | SLC22A12 (0.33) | SLC22A12CYP1A2 | |
| SCHEMBL28856544 | 0.76 | MAPT (0.34) | MAPTALDH1A1KDM4EKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |