Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856542 | 0.85 | ALDH1A1 (0.37) | SLC22A12AR | |
| SCHEMBL28955000 | 0.83 | HPGD (0.34) | SLC22A12 | |
| SCHEMBL28856553 | 0.83 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28856504 | 0.82 | SLC22A12 (0.33) | SLC22A12 | |
| SCHEMBL28856487 | 0.81 | GRM2 (0.31) | — | |
| SCHEMBL28856551 | 0.80 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28856496 | 0.78 | CA12 (0.39) | SLC22A12 | |
| SCHEMBL28856516 | 0.76 | KDM4E (0.33) | SLC22A12 | |
| SCHEMBL28856521 | 0.76 | SLC22A12 (0.33) | SLC22A12 | |
| SCHEMBL28856528 | 0.73 | SLC22A12 (0.57) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |