Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994223 | 0.82 | KDM4E (0.47) | NPC1PKMALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1498778 | 0.75 | TP53 (0.43) | NOTUMTP53L3MBTL1NPC1PKM | |
| SCHEMBL1670472 | 0.75 | GRN (0.56) | TP53KLKB1MAPTALDH1A1POLB | |
| SCHEMBL31537588 | 0.75 | TP53 (0.44) | TP53L3MBTL1NPC1PKMLMNA | |
| Hydrochloric Acid SCHEMBL34466698 | 0.73 | TP53 (0.42) | NOTUMTP53L3MBTL1NPC1PKM | |
| SCHEMBL31409379 | 0.73 | TP53 (0.42) | TP53L3MBTL1NPC1PKMKLKB1 | |
| SCHEMBL2254831 | 0.71 | RXRA (0.48) | ALDH1A1KDM4E | |
| SCHEMBL10164411 | 0.71 | KDM4E (0.44) | TP53L3MBTL1MAPTALDH1A1HSD17B10 | |
| SCHEMBL8253879 | 0.71 | KDM4E (0.46) | NPC1PKMMAPTALDH1A1HSD17B10 | |
| SCHEMBL24709688 | 0.70 | RORC (0.42) | TP53L3MBTL1KLKB1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244043-A | Benzimidazolonyl cinnamamide derivative as TRPV1 antagonist and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2022-10-25 | — | — | CN | disclosed |