Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766106 | 0.98 | ALDH1A1 (0.41) | ALDH1A1PKMHPGDGPR84KCNH2 | |
| SCHEMBL2364798 | 0.97 | ALDH1A1 (0.39) | ALDH1A1PKMHPGDGPR84KCNH2 | |
| SCHEMBL3404044 | 0.92 | HRH3 (0.38) | ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL3405755 | 0.84 | GLA (0.31) | — | |
| SCHEMBL651213 | 0.80 | GPR84 (0.41) | ALDH1A1PKMHPGDGPR84PI4KA | |
| Hydrochloric Acid SCHEMBL12468552 | 0.79 | GPR84 (0.40) | ALDH1A1PKMHPGDGPR84PI4KA | |
| SCHEMBL29882926 | 0.78 | GPR84 (0.30) | GPR84 | |
| SCHEMBL1134128 | 0.77 | — | — | |
| SCHEMBL28312249 | 0.76 | ALDH1A1 (0.39) | ALDH1A1PKMHPGDGPR84KCNH2 | |
| Bromide SCHEMBL28677053 | 0.76 | KCNH2 (0.48) | ALDH1A1PKMHPGDGPR84KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115312598-A | HEMT humidity-sensitive element for respiration monitoring and preparation method and application thereof | 大连理工大学 | 2022-11-08 | — | — | CN | claimed |
| CN-115312598-A | HEMT humidity-sensitive element for respiration monitoring and preparation method and application thereof | 大连理工大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-113205022-B | Respiratory anomaly monitoring method and system based on wavelet analysis | 湖南万脉医疗科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-113205022-A | Respiratory anomaly monitoring method and system based on wavelet analysis | 湖南万脉医疗科技有限公司 | 2021-08-03 | — | — | CN | disclosed |