Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958389 | 0.90 | MAPT (0.41) | MAPTLMNANPSR1ADAMTS5MMP2 | |
| SCHEMBL3870090 | 0.67 | HTR1A (0.69) | LMNAHTR1AHTR7SIGMAR1TSHR | |
| SCHEMBL3207003 | 0.66 | HTR1A (0.67) | HTR1AHTR7SIGMAR1 | |
| SCHEMBL1327430 | 0.65 | MAPT (0.82) | MAPTLMNANPSR1HTR1AHTR7 | |
| Phenylpiperazine SCHEMBL6495303 | 0.64 | SIGMAR1 (0.67) | MAPTLMNANPSR1HTR1AHTR7 | |
| SCHEMBL11247532 | 0.64 | KCNH2 (0.73) | HTR1AHTR7SIGMAR1 | |
| SCHEMBL11260878 | 0.64 | KCNH2 (0.73) | HTR1AHTR7SIGMAR1 | |
| SCHEMBL4172010 | 0.64 | MAPT (0.68) | MAPTNPSR1HTR1AHTR7ALDH1A1 | |
| Butyramide SCHEMBL27930337 | 0.62 | SMN1; SMN2 (0.55) | MAPTLMNANPSR1ALDH1A1SIGMAR1 | |
| SCHEMBL9685878 | 0.62 | MAPT (0.43) | MAPTLMNANPSR1ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234631-B | Composition for treating hypertension and/or fibrosis | 维克特斯生物系统有限公司 | 2023-02-28 | — | — | CN | disclosed |