Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958296 | 0.90 | MAPT (0.40) | MAPTLMNANPSR1ADAMTS5MMP2 | |
| SCHEMBL9685878 | 0.72 | MAPT (0.43) | MAPTLMNANPSR1ADAMTS5MMP2 | |
| SCHEMBL2114983 | 0.65 | HTR1A (0.73) | MAPTLMNAHTR1AHTR7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9811592 | 0.64 | HTR1A (0.71) | MAPTLMNAHTR1AHTR7ALDH1A1 | |
| SCHEMBL27786793 | 0.64 | MAPT (0.78) | MAPTLMNANPSR1HTR1AHTR7 | |
| SCHEMBL4432092 | 0.63 | HDAC1 (0.63) | MAPTLMNANPSR1HTR1AALDH1A1 | |
| SCHEMBL8045431 | 0.63 | KCNH2 (0.69) | HTR1AHTR7SIGMAR1 | |
| SCHEMBL8484287 | 0.62 | MAOA (0.50) | LMNANPSR1MEN1KMT2ATSHR | |
| SCHEMBL8343570 | 0.62 | HDAC3 (0.62) | MAPTLMNANPSR1ALDH1A1MEN1 | |
| SCHEMBL30528252 | 0.61 | MAPT (0.86) | MAPTLMNANPSR1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234631-B | Composition for treating hypertension and/or fibrosis | 维克特斯生物系统有限公司 | 2023-02-28 | — | — | CN | disclosed |