Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP9X | Q93008 | 3/20 | 0.40 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005033 | 0.91 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 | |
| SCHEMBL21004644 | 0.79 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 | |
| SCHEMBL25771124 | 0.78 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 | |
| SCHEMBL21151389 | 0.77 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 | |
| SCHEMBL21005032 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1USP9XKDM2B | |
| SCHEMBL21004687 | 0.77 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 | |
| SCHEMBL20970262 | 0.76 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1USP9XPSEN1 | |
| SCHEMBL20970260 | 0.76 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1USP9XPSEN1 | |
| SCHEMBL20970271 | 0.76 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1USP9XPSEN1 | |
| Hydrochloric Acid SCHEMBL20511341 | 0.76 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1USP9XDHCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304605-B | Oxetane derivatives with antitumor activity, and preparation method and application thereof | 陕西国际商贸学院 | 2023-10-03 | — | — | CN | disclosed |
| CN-115304605-A | Oxetane derivative with anti-tumor activity and preparation method and application thereof | 陕西国际商贸学院 | 2022-11-08 | — | — | CN | disclosed |