Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639160 | 0.80 | MAPT (0.48) | KDM4EMAPTNPC1RAB9AALOX15 | |
| SCHEMBL9724293 | 0.71 | GAA (0.43) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL29293278 | 0.70 | PDE3B (0.41) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7724178 | 0.69 | CA12 (0.48) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL549144 | 0.69 | MAPK1 (0.54) | KDM4EMAPTALOX15KMT2AMAOB | |
| SCHEMBL7678910 | 0.69 | GAA (0.40) | KDM4EMAPTNPC1RAB9AALOX15 | |
| SCHEMBL9178589 | 0.68 | MAPT (0.51) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL235046 | 0.67 | TSHR (0.60) | KDM4EMAPTALOX15KMT2AMAOB | |
| SCHEMBL20774535 | 0.67 | RPS6KA3 (0.48) | KDM4EMAPTALOX15ALPLMAOB | |
| SCHEMBL11679386 | 0.67 | MAOB (0.41) | KDM4EMAPTNPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920208-B | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-11-08 | — | — | CN | claimed |
| CN-112920208-B | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-11-08 | — | — | CN | disclosed |