Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866854 | 0.90 | MEN1 (0.47) | MEN1MAPTKMT2AG6PDCRHBP | |
| SCHEMBL28567895 | 0.90 | L3MBTL1 (0.59) | MEN1MAPTKMT2AG6PDCRHBP | |
| SCHEMBL22720165 | 0.84 | KDM4E (0.60) | MEN1MAPTKMT2AKDM4EASPH | |
| SCHEMBL16737117 | 0.83 | MAPT (0.51) | MEN1MAPTKMT2AKDM4EASPH | |
| SCHEMBL11192184 | 0.82 | LMNA (0.57) | MEN1MAPTKMT2AKDM4EASPH | |
| SCHEMBL21248493 | 0.79 | L3MBTL1 (0.55) | MEN1MAPTKMT2AKDM4EASPH | |
| SCHEMBL21248559 | 0.79 | L3MBTL1 (0.55) | MEN1KMT2AG6PDCRHBPCRHR2 | |
| SCHEMBL21248517 | 0.79 | L3MBTL1 (0.55) | MEN1MAPTKMT2AKDM4EASPH | |
| SCHEMBL16489005 | 0.79 | AKR1C3 (0.67) | MEN1MAPTKMT2AKDM4EGRIK1 | |
| SCHEMBL28965118 | 0.79 | G6PD (0.55) | MEN1MAPTKMT2AG6PDCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557890-B | Polysubstituted acridone alkyl derivative and preparation method and application thereof | 宁波大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-115557890-A | Polysubstituted acridone alkyl derivative and preparation method and application thereof | 宁波大学 | 2023-01-03 | — | — | CN | disclosed |