Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236955 | 0.82 | SIGMAR1 (0.43) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL17275990 | 0.79 | OPRD1 (0.39) | OPRD1SIGMAR1CHRM5CHRM3OPRM1 | |
| SCHEMBL30131686 | 0.73 | OPRD1 (0.41) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL27667325 | 0.72 | SIGMAR1 (0.44) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL1401532 | 0.72 | SIGMAR1 (0.38) | OPRD1SIGMAR1SLC6A4 | |
| SCHEMBL2764645 | 0.72 | SIGMAR1 (0.38) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL28716337 | 0.72 | LMNA (0.45) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL28706411 | 0.72 | LMNA (0.45) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL13484571 | 0.71 | SIGMAR1 (0.44) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL1494478 | 0.71 | SIGMAR1 (0.43) | OPRD1SIGMAR1CHRM5CHRM3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |