Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165312 | 0.83 | OPRK1 (0.46) | OPRK1LMNAMEN1KMT2ATACR1 | |
| SCHEMBL17165313 | 0.81 | OPRK1 (0.36) | OPRK1LMNAMEN1KMT2ATACR1 | |
| SCHEMBL28883299 | 0.79 | OPRK1 (0.49) | OPRK1LMNAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18488424 | 0.77 | OPRK1 (0.42) | OPRK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18472605 | 0.76 | OPRK1 (0.39) | OPRK1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18488421 | 0.76 | MTNR1A (0.47) | OPRK1MEN1KMT2A | |
| SCHEMBL28883458 | 0.76 | SCN9A (0.48) | OPRK1ALDH1A1KMT2ATACR1 | |
| SCHEMBL18472622 | 0.76 | MTNR1A (0.47) | OPRK1MEN1KMT2A | |
| SCHEMBL5991851 | 0.76 | ALDH1A1 (0.49) | OPRK1LMNACTSGCMA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5992886 | 0.75 | KMT2A (0.48) | OPRK1LMNACTSGCMA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340468-A | (R) -deuterated phenylalanine derivative and preparation method thereof | 西南大学 | 2022-11-15 | — | — | CN | disclosed |