Methyl Alcohol

Methyl Alcohol

SCHEMBL28958779

CO.Cc1ccc(C(=O)C(Cl)Cl)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.55
ALDH1A1 P00352 5/20 0.52
CES2 O00748 3/20 0.52
CES1 P23141 3/20 0.52
LMNA P02545 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
HPGD P15428 3/20 0.48
PKM P14618 2/20 0.46
HTT P42858 2/20 0.46
ATM Q13315 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
NLRP1 Q9C000 1/20 0.46
GAA P10253 1/20 0.46
NTSR1 P30989 1/20 0.46
SRD5A2 P31213 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7768899 0.98 PDPK1 (0.57) PDPK1ALDH1A1CES2CES1LMNA
SCHEMBL31186169 0.85 PDPK1 (0.70) PDPK1CES2CES1LMNASMN1; SMN2
SCHEMBL10384383 0.82 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL8388071 0.80 ALDH1A1 (0.50) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL14369396 0.79 PDPK1 (0.57) PDPK1ALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL11749506 0.78 SMN1; SMN2 (0.48) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL11599419 0.78 SMN1; SMN2 (0.48) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL2233657 0.78 ALDH1A1 (0.59) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7457651 0.77 SMN1; SMN2 (0.47) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL6851984 0.76 PDPK1 (0.59) PDPK1ALDH1A1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724727-A Method for preparing cyazofamid intermediate 2,2-dichloro-4' -methylacetophenone 河北工业职业技术学院 2023-03-03 CN disclosed