Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696515 | 0.82 | GSK3B (0.61) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL7768899 | 0.82 | PDPK1 (0.57) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| Methyl Alcohol SCHEMBL28958779 | 0.80 | PDPK1 (0.55) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL633160 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL10384383 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL1481505 | 0.80 | CES2 (0.52) | ALDH1A1CES2CES1LMNAMEN1 | |
| SCHEMBL28636492 | 0.80 | CES2 (0.52) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL28075917 | 0.78 | CES2 (0.50) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL28121319 | 0.78 | GSK3B (0.42) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL27650405 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869683-A | Processes for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0705823-A1 | Process for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |